aeruginosa growth and dispersal on surfaces. Here we identified a stochastic genetic switch, hecR–hecE, which is expressed bimodally and generates functionally distinct bacterial subpopulations to balance P. Urs Jenal ORCID: /0000-0002-1637-3376 1Įfficient colonization of mucosal surfaces is essential for opportunistic pathogens like Pseudomonas aeruginosa, but how bacteria collectively and individually adapt to optimize adherence, virulence and dispersal is largely unclear.

Open “ Sid Meiers Colonization” folder, double click on “Setup” and proceed install.Īfter installation complete, go to the “Installed Game” location.ĭouble click on “Colonization” icon to play the game.A genetic switch controls Pseudomonas aeruginosa surface colonization Video Card: 3D graphics card compatible with DirectX 8

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